Investigation of the Radial Ionization Distribution of Heavy Ions with an Optical Particle Track Chamber and Monte-Carlo Simulation (Dissertation)

 

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G. Laczkó

Investigation of the Radial Ionization Distribution of Heavy Ions with an Optical Particle Track Chamber and Monte-Carlo Simulation (Dissertation)

ISBN: 978-3-86509-634-0   |   Erscheinungsjahr: 2007    |    Auflage: 1
Seitenzahl: 172   |    Einband: Broschur    |    Gewicht: 470 g
Lieferzeit: 2-3 Tage
20,50 €
Inkl. 7% MwSt., zzgl. Versandkosten bei Auslandsbestellungen

Beams of charged particles like protons or heavy ions (ions heavier than protons are termed heavy ions in the usual terminology of radiobiology) represent a superior radiotherapeutic alternative for the treatment of deep-seated tumors compared to conventional photon beams. lon beams have an inverted depth dose profile: In contrast to the exponential dose deposition of conventional photon beams, the absorbed dose of ions increases with the penetration depth and shows a steep maximum (Bragg peak) and a sharp drop behind it. In addition, the relative biological effectiveness, RBE, of ions is higher than that of sparsely ionizing radiation, especially in the stopping region at the Bragg peak. Hence, the deposited energy and - even more pronounced due to the increased biological effectiveness - the cell killing effect have their maximum values not an the skin but in a deepness in the body that can be adjusted by varying the ion energy. This property of charged particles allows for an outstanding conformity and effectiveness of the applied radiation dose, if appropriate techniques of beam application and treatment planning are applied.

PTB N-54